Blood Results — December 2025

Assessment: Workplace health assessment
Blood report: 19 December 2025
Patient: Anthony G. | Age: 37 | Male | Weight: 94.6 kg | Height: 173 cm

Body Composition

Metric Result Range / Target Status Notes
Body Fat % 25.2% <20% ideal HIGH Relevant to exercise prescription; see research/Exercise as Medicine for AuDHD-HFE
Visceral Fat Rating 11 <12 Normal Borderline — monitor
Muscle Mass 67.3 kg — Moderate Muscle is a major iron sink; more = better for HFE
Total Body Water % 50.5% 55%+ LOW Chronic dehydration — affects iron metabolism and kidney function
BMR 1,898 kcal — —
Estimated Daily Calories 2,658 kcal — — May be reduced by Elvanse appetite suppression

Cardiovascular

Metric Result Range Status Notes
Systolic BP 122 mmHg <130 Normal
Diastolic BP 79 mmHg <85 Normal
Resting Heart Rate 88 bpm 60–80 HIGH Supports autonomic dysfunction hypothesis; see research/Autonomic Nervous System and Vagal Tone in AuDHD
Waist/Hip Ratio 0.8 <0.90 Low risk
QRISK3 (10-yr CV risk) 0.9% Low Low
Heart Age 37 years — Normal Matches chronological age

RHR of 88 bpm is clinically notable. Possible contributors: iron-related cardiac effects, low vagal tone (AuDHD autonomic pattern), deconditioning, chronic dehydration, or Elvanse sympathomimetic effect. HRV assessment would clarify.

Iron & Ferritin

Test Result Range (Male <40) Status Notes
Serum Iron 26.0 µmol/L 10–30 Normal Mid-range here; rose to 32 by March 2026
Serum Ferritin 738 µg/L 30–442 HIGH Confirms the "~700" referenced in March notes was actually 738

This is the baseline before dietary changes took effect. By March 2026, ferritin dropped to 380 — a 48% reduction in ~3 months from diet alone. TSAT and UIBC were not tested in December.

Thyroid Function

Test Result Range Status Notes
TSH 1.440 mIU/L 0.27–4.20 Normal Mid-range — no pituitary suppression
Free T3 6.3 pmol/L 3.1–6.8 Normal Upper range — T4→T3 conversion intact
Free T4 19.2 pmol/L 12.0–22.0 Normal Upper-normal

Thyroid axis is clear. Despite iron overload's theoretical risk to thyroid function, TSH/fT3/fT4 are all solidly normal. This rules out thyroid as a contributor to fatigue. No need for repeat thyroid testing unless symptoms change. See research/Endocrine Effects of HFE Iron Overload.

Blood Glucose & Diabetes

Test Result Range Status Notes
Blood Glucose (fasting) 5.7 mmol/L <6.0 Normal Upper-normal — worth monitoring given HFE diabetes risk
HbA1c 30 mmol/mol <42 Normal Well within non-diabetic range

Diabetes ruled out for now. HbA1c of 30 is excellent. However, fasting glucose at 5.7 is upper-normal (pre-diabetic threshold is 5.6–6.9 for IFG). With ferritin 738, continued monitoring is wise. See research/Endocrine Effects of HFE Iron Overload.

Vitamins

Test Result Range Status Notes
Active Vitamin B12 119.0 pmol/L 37.5–188.0 Normal Mid-range
Serum Folate 6.8 nmol/L >7.0 LOW Below range despite folic acid supplementation

Low folate despite supplementation is a red flag. This strongly suggests either:

  1. MTHFR variant preventing conversion of folic acid to active methylfolate — MTHFR testing is now the highest priority genetic test
  2. Inadequate dose or poor absorption
  3. Elvanse appetite suppression reducing dietary folate intake

Action: Switch from folic acid to methylfolate (5-MTHF) 400–800 µg/day immediately as a precautionary measure, even before MTHFR results. If MTHFR C677T homozygous, methylfolate is essential. See Genetic Architecture of AuDHD, Diet and Supplement Strategy.

Liver Function

Test Result Range Status
Total Protein 85 g/L 60–80 Slightly HIGH
Albumin 52 g/L 35–50 Slightly HIGH
Globulin 34 g/L 19–35 Normal
ALT 29 U/L 5–45 Normal
ALP 67 IU/L 30–130 Normal
GGT 26 U/L 5–55 Normal
Total Bilirubin 8 µmol/L <22 Normal

Liver enzymes (ALT, GGT, ALP) all normal — reassuring that ferritin 738 has not yet caused detectable hepatocellular damage. Elevated total protein and albumin likely reflect dehydration (consistent with low body water 50.5%) rather than pathology. By March 2026: total protein dropped to 76, albumin to 48 (both normal) — supporting the dehydration hypothesis.

Kidney Function

Test Result Range Status
Sodium 136 mmol/L 133–146 Normal
Urea 8.6 mmol/L 2.5–7.8 Slightly HIGH
Creatinine 104 µmol/L 60–120 Normal
eGFR 82 ml/min >60 Normal

Mildly elevated urea with normal creatinine and eGFR most likely reflects dehydration (consistent with body water 50.5% and elevated protein/albumin). Not a kidney concern, but a hydration concern.

Full Blood Count

Red Cells

Test Result Range Status
Haemoglobin 168 g/L 130–180 Normal
Red Cell Count 5.37 ×10¹²/L 4.4–6.5 Normal
MCV 90.7 fL 80–100 Normal
MCH 31.2 pg 27.0–32.0 Normal
MCHC 344 g/L 320–360 Normal
RDW 13.7% — —

Hb 168 is adequate for phlebotomy (threshold typically >120). Normal MCV rules out macrocytic anaemia from folate deficiency — though folate is borderline low.

Platelets

Test Result Range Status
Platelets 289 ×10⁹/L 150–450 Normal
MPV 8.7 fL — —

White Cells

Test Result Range Status
White Cell Count 5.3 ×10⁹/L 3.0–11.0 Normal
Neutrophils 2.8 ×10⁹/L 2.0–7.5 Normal
Lymphocytes 2.14 ×10⁹/L 1.5–4.5 Normal
Monocytes 0.27 ×10⁹/L 0.2–0.8 Normal
Eosinophils 0.06 ×10⁹/L 0–0.4 Normal
Basophils 0.010 ×10⁹/L 0–0.11 Normal

FBC is entirely normal. No signs of infection, inflammation, or bone marrow suppression.

Bone Screen & Prostate

Test Result Range Status
Calcium 2.47 mmol/L 2.2–2.6 Normal
PSA 1.25 µg/L <2.6 Normal

Urinalysis — All Normal

No blood, protein, glucose, ketones, nitrites, or leukocytes detected.

Longitudinal Tracking

Marker Dec 2025 Mar 2026 Change Notes
Ferritin 738 µg/L 380 µg/L ↓ 48% Diet effective; phlebotomy still needed
Serum Iron 26.0 µmol/L 32 µmol/L ↑ 23% Rose despite diet — at ceiling by March
TSAT Not tested 60% — Above NTBI threshold
Total Protein 85 g/L 76 g/L ↓ Normalised Likely hydration improvement
Albumin 52 g/L 48 g/L ↓ Normalised Likely hydration improvement
ALT 29 U/L 27 U/L Stable Liver preserved

What This Changes

Tests No Longer Needed

Tests Now More Urgent

  1. MTHFR genotyping — folate low despite supplementation. Highest priority genetic test.
  2. Testosterone panel — only remaining untested endocrine axis (no testosterone in this panel)
  3. Vitamin D — still untested across both panels
  4. TSAT — not in Dec panel; the 60% in March is the key risk marker

Revised Medichecks Strategy

Given Dec 2025 results, the optimal Medichecks purchase is now:

Alternatively, the Optimal Health test (£249) still has value for the lipid detail, hs-CRP, and comprehensive panel — but the thyroid/HbA1c/B12 components would be redundant.

Cross-References